Estimation Of The Effectiveness Of Hyposensitizing Immunotherapy By Bronchial Asthma Micro-Mite Etiology In Children Of The Republic Of Uzbekistan

Abstract

This article presents the results of evaluating the therapeutic efficacy of specific allergic vaccination in 77 children with allergy of micro-mite etiology.  The age of children was in the range of 7-14 years, including 7-12 years old - 29 (37.7%), 12-14 years old - 48 (62.3%).

In general, of the total number of patients (77) who received specific treatment, excellent results were observed in 26 (33.7–4.2%). In this group of patients, after treatment, all the main symptoms of the disease completely disappeared. Good results were observed in 39 (50.6–4.4) patients. In this group of patients, most of the symptoms of the disease disappeared or the intensity of their severity was weakened. Satisfactory results were observed in 11.7% of patients. In this group of patients, the symptoms of the disease remained, but the intensity of their manifestation was weakened. In 3.9% of patients, the treatment effect was absent. It turned out that the therapeutic effectiveness of specific therapy lasts for 1-3 years. So, good and excellent results were achieved after 1 year - 62.8%, after 2 years - 55.4%, and after 3 years - 50.0%.

The use of a new method of allergen-specific immunotherapy of children suffering from allergic diseases: the combined method (inhalation of the allergen + its electrophoresis through the skin) of immunotherapy compares favorably with the known traditional (multiple injection methods) with great therapeutic efficiency, does not cause negative side local and general reactions, does not give complications, lengthen remission.